STEM CELLS MADE FROM SKIN USED TO GENERATE NEW BRAIN CELLS
UCI-led study to advance understanding of the role of microglia in Alzheimer’s disease
Irvine, Calif., (April 25, 2017) — Using human skin cells, University of California, Irvine neurobiologists and their colleagues have created a method to generate one of the principle cell types of the brain called microglia, which play a key role in preserving the function of neural networks and responding to injury and disease.
The finding marks an important step in the use of induced pluripotent stem (iPS) cells for targeted approaches to better understand and potentially treat neurological diseases such as Alzheimer’s. These iPS cells are derived from existing adult skin cells and show increasing utility as a promising approach for studying human disease and developing new therapies. Continue reading